Influenza burden in children newborn to eleven months of age in a pediatric emergency department during the peak of an influenza epidemic.
Identifieur interne : 000258 ( France/Analysis ); précédent : 000257; suivant : 000259Influenza burden in children newborn to eleven months of age in a pediatric emergency department during the peak of an influenza epidemic.
Auteurs : D. Ploin [France] ; S. Liberas [France] ; D. Thouvenot [France] ; A. Fouilhoux [France] ; Y. Gillet [France] ; A. Denis [France] ; F. Chapuis [France] ; B. Lina [France] ; D. Floret [France]Source :
Descripteurs français
- Wicri :
- topic : Statistique.
English descriptors
- mix :
- Age Factors, Disease Outbreaks, Emergency Service, Female, Follow-Up Studies, France/epidemiology, Hospital, Hospitalization/*statistics & numerical data, Human/*diagnosis/*epidemiology, Humans, Incidence, Infant, Influenza, Male, Newborn, Nonparametric, Prospective Studies, Sampling Studies, Severity of Illness Index, Statistics.
Abstract
BACKGROUND: The aim of this study was to determine the burden of influenza-related diseases in children 0 to 11 months of age during the peak of the 2001 to 2002 influenza epidemic. METHODS: This was a prospective study at the Pediatric Emergency Department of Edouard Herriot tertiary teaching hospital in Lyon, France. The study included 304 infants 0 to 11 months of age. Consecutive patients were systematically enrolled during the 4 weeks of the influenza epidemic peak (Weeks 3 to 6, 2002). Influenza viruses were detected by antigen detection and virus culture from nasal swabs. Structured telephone interviews were conducted on Days 8 and 15 after virus detection. There was also a 6-month survey into the medicoadministrative database to detect late complications that required delayed hospitalization of influenza-positive children. RESULTS: Influenza virus was detected in 99 (33%) of 304 patients (A/H3N2 in 30% and B in 3%). Nonrespiratory symptoms were the dominant clinical manifestations in 30% of influenza-positive children. One child with influenza presented with febrile seizures. Twenty (20%) children with influenza were hospitalized. Parents reported recovery from the illness in 63 and 94% of children on Days 8 and 15, respectively. The median length of an influenza episode was 8 days. CONCLUSIONS: Our results confirm the high prevalence of influenza-related morbidity in infants during the epidemic peak. One child in three consulting to the pediatric emergency room had a virologically confirmed influenza infection regardless of the body temperature. Every fifth child with influenza was admitted to hospital, which corresponds to an admission rate of 237 per 100 000 children 0 to 11 months of age.
Url:
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000166
- to stream Hal, to step Curation: 000166
- to stream Hal, to step Checkpoint: 000332
- to stream Main, to step Merge: 001776
- to stream Main, to step Curation: 001740
- to stream Main, to step Exploration: 001740
- to stream France, to step Extraction: 000258
Links to Exploration step
Hal:hal-00122898Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influenza burden in children newborn to eleven months of age in a pediatric emergency department during the peak of an influenza epidemic.</title><author><name sortKey="Ploin, D" sort="Ploin, D" uniqKey="Ploin D" first="D." last="Ploin">D. Ploin</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26649" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de Lyon</orgName> <desc> <address> <addrLine>69 Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-308395" type="direct"></relation> <relation active="#struct-308396" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-308395" type="direct"><org type="institution" xml:id="struct-308395" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-308396" type="direct"><org type="institution" xml:id="struct-308396" status="INCOMING"> <orgName>Lyon</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Liberas, S" sort="Liberas, S" uniqKey="Liberas S" first="S." last="Liberas">S. Liberas</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Thouvenot, D" sort="Thouvenot, D" uniqKey="Thouvenot D" first="D." last="Thouvenot">D. Thouvenot</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-714" status="OLD"> <orgName>Virologie et pathogenèse virale</orgName> <orgName type="acronym">VPV</orgName> <date type="end">2006-12-31</date> <desc> <address> <addrLine>Faculté de Médecine RTH Laennec Rue Guillaume Paradin 69372 LYON CEDEX 08</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation name="UMR5537" active="#struct-441569" type="direct"></relation> <relation active="#struct-194495" type="direct"></relation> <relation active="#struct-301088" type="indirect"></relation> </listRelation> <tutelles><tutelle name="UMR5537" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno> <idno type="ISNI">0000000122597504</idno> <orgName>Centre National de la Recherche Scientifique</orgName> <orgName type="acronym">CNRS</orgName> <date type="start">1939-10-19</date> <desc> <address> <country key="FR"></country> </address> <ref type="url">http://www.cnrs.fr/</ref> </desc> </org></tutelle><tutelle active="#struct-194495" type="direct"><org type="institution" xml:id="struct-194495" status="VALID"> <idno type="IdRef">026402823</idno> <idno type="ISNI">0000000121686185</idno> <orgName>Université Claude Bernard Lyon 1</orgName> <orgName type="acronym">UCBL</orgName> <desc> <address> <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-lyon1.fr/</ref> </desc> <listRelation> <relation active="#struct-301088" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-301088" type="indirect"><org type="regroupinstitution" xml:id="struct-301088" status="VALID"> <orgName>Université de Lyon</orgName> <desc> <address> <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine> <country key="FR"></country> </address> <ref type="url">https://www.universite-lyon.fr/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Lyon</settlement><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Rhône-Alpes</region></placeName><orgName type="university">Université Claude Bernard Lyon 1</orgName><orgName type="institution" wicri:auto="newGroup">Université de Lyon</orgName></affiliation></author><author><name sortKey="Fouilhoux, A" sort="Fouilhoux, A" uniqKey="Fouilhoux A" first="A." last="Fouilhoux">A. Fouilhoux</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Gillet, Y" sort="Gillet, Y" uniqKey="Gillet Y" first="Y." last="Gillet">Y. Gillet</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Denis, A" sort="Denis, A" uniqKey="Denis A" first="A." last="Denis">A. Denis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26649" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de Lyon</orgName> <desc> <address> <addrLine>69 Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-308395" type="direct"></relation> <relation active="#struct-308396" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-308395" type="direct"><org type="institution" xml:id="struct-308395" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-308396" type="direct"><org type="institution" xml:id="struct-308396" status="INCOMING"> <orgName>Lyon</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Chapuis, F" sort="Chapuis, F" uniqKey="Chapuis F" first="F." last="Chapuis">F. Chapuis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26649" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de Lyon</orgName> <desc> <address> <addrLine>69 Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-308395" type="direct"></relation> <relation active="#struct-308396" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-308395" type="direct"><org type="institution" xml:id="struct-308395" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-308396" type="direct"><org type="institution" xml:id="struct-308396" status="INCOMING"> <orgName>Lyon</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Lina, B" sort="Lina, B" uniqKey="Lina B" first="B." last="Lina">B. Lina</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-714" status="OLD"> <orgName>Virologie et pathogenèse virale</orgName> <orgName type="acronym">VPV</orgName> <date type="end">2006-12-31</date> <desc> <address> <addrLine>Faculté de Médecine RTH Laennec Rue Guillaume Paradin 69372 LYON CEDEX 08</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation name="UMR5537" active="#struct-441569" type="direct"></relation> <relation active="#struct-194495" type="direct"></relation> <relation active="#struct-301088" type="indirect"></relation> </listRelation> <tutelles><tutelle name="UMR5537" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno> <idno type="ISNI">0000000122597504</idno> <orgName>Centre National de la Recherche Scientifique</orgName> <orgName type="acronym">CNRS</orgName> <date type="start">1939-10-19</date> <desc> <address> <country key="FR"></country> </address> <ref type="url">http://www.cnrs.fr/</ref> </desc> </org></tutelle><tutelle active="#struct-194495" type="direct"><org type="institution" xml:id="struct-194495" status="VALID"> <idno type="IdRef">026402823</idno> <idno type="ISNI">0000000121686185</idno> <orgName>Université Claude Bernard Lyon 1</orgName> <orgName type="acronym">UCBL</orgName> <desc> <address> <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-lyon1.fr/</ref> </desc> <listRelation> <relation active="#struct-301088" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-301088" type="indirect"><org type="regroupinstitution" xml:id="struct-301088" status="VALID"> <orgName>Université de Lyon</orgName> <desc> <address> <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine> <country key="FR"></country> </address> <ref type="url">https://www.universite-lyon.fr/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Lyon</settlement><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Rhône-Alpes</region></placeName><orgName type="university">Université Claude Bernard Lyon 1</orgName><orgName type="institution" wicri:auto="newGroup">Université de Lyon</orgName></affiliation></author><author><name sortKey="Floret, D" sort="Floret, D" uniqKey="Floret D" first="D." last="Floret">D. Floret</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:hal-00122898</idno><idno type="halId">hal-00122898</idno><idno type="halUri">https://hal.archives-ouvertes.fr/hal-00122898</idno><idno type="url">https://hal.archives-ouvertes.fr/hal-00122898</idno><date when="2003">2003</date><idno type="wicri:Area/Hal/Corpus">000166</idno><idno type="wicri:Area/Hal/Curation">000166</idno><idno type="wicri:Area/Hal/Checkpoint">000332</idno><idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000332</idno><idno type="wicri:Area/Main/Merge">001776</idno><idno type="wicri:Area/Main/Curation">001740</idno><idno type="wicri:Area/Main/Exploration">001740</idno><idno type="wicri:Area/France/Extraction">000258</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Influenza burden in children newborn to eleven months of age in a pediatric emergency department during the peak of an influenza epidemic.</title><author><name sortKey="Ploin, D" sort="Ploin, D" uniqKey="Ploin D" first="D." last="Ploin">D. Ploin</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26649" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de Lyon</orgName> <desc> <address> <addrLine>69 Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-308395" type="direct"></relation> <relation active="#struct-308396" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-308395" type="direct"><org type="institution" xml:id="struct-308395" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-308396" type="direct"><org type="institution" xml:id="struct-308396" status="INCOMING"> <orgName>Lyon</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Liberas, S" sort="Liberas, S" uniqKey="Liberas S" first="S." last="Liberas">S. Liberas</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Thouvenot, D" sort="Thouvenot, D" uniqKey="Thouvenot D" first="D." last="Thouvenot">D. Thouvenot</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-714" status="OLD"> <orgName>Virologie et pathogenèse virale</orgName> <orgName type="acronym">VPV</orgName> <date type="end">2006-12-31</date> <desc> <address> <addrLine>Faculté de Médecine RTH Laennec Rue Guillaume Paradin 69372 LYON CEDEX 08</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation name="UMR5537" active="#struct-441569" type="direct"></relation> <relation active="#struct-194495" type="direct"></relation> <relation active="#struct-301088" type="indirect"></relation> </listRelation> <tutelles><tutelle name="UMR5537" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno> <idno type="ISNI">0000000122597504</idno> <orgName>Centre National de la Recherche Scientifique</orgName> <orgName type="acronym">CNRS</orgName> <date type="start">1939-10-19</date> <desc> <address> <country key="FR"></country> </address> <ref type="url">http://www.cnrs.fr/</ref> </desc> </org></tutelle><tutelle active="#struct-194495" type="direct"><org type="institution" xml:id="struct-194495" status="VALID"> <idno type="IdRef">026402823</idno> <idno type="ISNI">0000000121686185</idno> <orgName>Université Claude Bernard Lyon 1</orgName> <orgName type="acronym">UCBL</orgName> <desc> <address> <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-lyon1.fr/</ref> </desc> <listRelation> <relation active="#struct-301088" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-301088" type="indirect"><org type="regroupinstitution" xml:id="struct-301088" status="VALID"> <orgName>Université de Lyon</orgName> <desc> <address> <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine> <country key="FR"></country> </address> <ref type="url">https://www.universite-lyon.fr/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Lyon</settlement><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Rhône-Alpes</region></placeName><orgName type="university">Université Claude Bernard Lyon 1</orgName><orgName type="institution" wicri:auto="newGroup">Université de Lyon</orgName></affiliation></author><author><name sortKey="Fouilhoux, A" sort="Fouilhoux, A" uniqKey="Fouilhoux A" first="A." last="Fouilhoux">A. Fouilhoux</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Gillet, Y" sort="Gillet, Y" uniqKey="Gillet Y" first="Y." last="Gillet">Y. Gillet</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Denis, A" sort="Denis, A" uniqKey="Denis A" first="A." last="Denis">A. Denis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26649" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de Lyon</orgName> <desc> <address> <addrLine>69 Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-308395" type="direct"></relation> <relation active="#struct-308396" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-308395" type="direct"><org type="institution" xml:id="struct-308395" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-308396" type="direct"><org type="institution" xml:id="struct-308396" status="INCOMING"> <orgName>Lyon</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Chapuis, F" sort="Chapuis, F" uniqKey="Chapuis F" first="F." last="Chapuis">F. Chapuis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26649" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de Lyon</orgName> <desc> <address> <addrLine>69 Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-308395" type="direct"></relation> <relation active="#struct-308396" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-308395" type="direct"><org type="institution" xml:id="struct-308395" status="INCOMING"> <orgName>Departement d'Information Medicale des Hospices Civils de</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-308396" type="direct"><org type="institution" xml:id="struct-308396" status="INCOMING"> <orgName>Lyon</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Lina, B" sort="Lina, B" uniqKey="Lina B" first="B." last="Lina">B. Lina</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-714" status="OLD"> <orgName>Virologie et pathogenèse virale</orgName> <orgName type="acronym">VPV</orgName> <date type="end">2006-12-31</date> <desc> <address> <addrLine>Faculté de Médecine RTH Laennec Rue Guillaume Paradin 69372 LYON CEDEX 08</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation name="UMR5537" active="#struct-441569" type="direct"></relation> <relation active="#struct-194495" type="direct"></relation> <relation active="#struct-301088" type="indirect"></relation> </listRelation> <tutelles><tutelle name="UMR5537" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno> <idno type="ISNI">0000000122597504</idno> <orgName>Centre National de la Recherche Scientifique</orgName> <orgName type="acronym">CNRS</orgName> <date type="start">1939-10-19</date> <desc> <address> <country key="FR"></country> </address> <ref type="url">http://www.cnrs.fr/</ref> </desc> </org></tutelle><tutelle active="#struct-194495" type="direct"><org type="institution" xml:id="struct-194495" status="VALID"> <idno type="IdRef">026402823</idno> <idno type="ISNI">0000000121686185</idno> <orgName>Université Claude Bernard Lyon 1</orgName> <orgName type="acronym">UCBL</orgName> <desc> <address> <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-lyon1.fr/</ref> </desc> <listRelation> <relation active="#struct-301088" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-301088" type="indirect"><org type="regroupinstitution" xml:id="struct-301088" status="VALID"> <orgName>Université de Lyon</orgName> <desc> <address> <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine> <country key="FR"></country> </address> <ref type="url">https://www.universite-lyon.fr/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Lyon</settlement><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Rhône-Alpes</region></placeName><orgName type="university">Université Claude Bernard Lyon 1</orgName><orgName type="institution" wicri:auto="newGroup">Université de Lyon</orgName></affiliation></author><author><name sortKey="Floret, D" sort="Floret, D" uniqKey="Floret D" first="D." last="Floret">D. Floret</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-26651" status="VALID"> <orgName>Service d'urgence et de réanimation pédiatriques [Hôpital Edouard Herriot - HCL]</orgName> <desc> <address> <addrLine>Lyon</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300094" type="direct"></relation> <relation active="#struct-300074" type="indirect"></relation> </listRelation> <tutelles><tutelle active="#struct-300094" type="direct"><org type="institution" xml:id="struct-300094" status="VALID"> <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName> <desc> <address> <addrLine>5 Place d'Arsonval69003 Lyon</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref> </desc> <listRelation> <relation active="#struct-300074" type="direct"></relation> </listRelation> </org></tutelle><tutelle active="#struct-300074" type="indirect"><org type="regroupinstitution" xml:id="struct-300074" status="VALID"> <idno type="IdRef">026534657</idno> <orgName>Hospices Civils de Lyon</orgName> <orgName type="acronym">HCL</orgName> <desc> <address> <addrLine>3 Quai des Célestins69002 Lyon </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author></analytic></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Age Factors</term><term>Disease Outbreaks</term><term>Emergency Service</term><term>Female</term><term>Follow-Up Studies</term><term>France/epidemiology</term><term>Hospital</term><term>Hospitalization/*statistics & numerical data</term><term>Human/*diagnosis/*epidemiology</term><term>Humans</term><term>Incidence</term><term>Infant</term><term>Influenza</term><term>Male</term><term>Newborn</term><term>Nonparametric</term><term>Prospective Studies</term><term>Sampling Studies</term><term>Severity of Illness Index</term><term>Statistics</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Statistique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"> <p>BACKGROUND: The aim of this study was to determine the burden of influenza-related diseases in children 0 to 11 months of age during the peak of the 2001 to 2002 influenza epidemic. METHODS: This was a prospective study at the Pediatric Emergency Department of Edouard Herriot tertiary teaching hospital in Lyon, France. The study included 304 infants 0 to 11 months of age. Consecutive patients were systematically enrolled during the 4 weeks of the influenza epidemic peak (Weeks 3 to 6, 2002). Influenza viruses were detected by antigen detection and virus culture from nasal swabs. Structured telephone interviews were conducted on Days 8 and 15 after virus detection. There was also a 6-month survey into the medicoadministrative database to detect late complications that required delayed hospitalization of influenza-positive children. RESULTS: Influenza virus was detected in 99 (33%) of 304 patients (A/H3N2 in 30% and B in 3%). Nonrespiratory symptoms were the dominant clinical manifestations in 30% of influenza-positive children. One child with influenza presented with febrile seizures. Twenty (20%) children with influenza were hospitalized. Parents reported recovery from the illness in 63 and 94% of children on Days 8 and 15, respectively. The median length of an influenza episode was 8 days. CONCLUSIONS: Our results confirm the high prevalence of influenza-related morbidity in infants during the epidemic peak. One child in three consulting to the pediatric emergency room had a virologically confirmed influenza infection regardless of the body temperature. Every fifth child with influenza was admitted to hospital, which corresponds to an admission rate of 237 per 100 000 children 0 to 11 months of age.</p> </div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Rhône-Alpes</li></region><settlement><li>Lyon</li></settlement><orgName><li>Université Claude Bernard Lyon 1</li><li>Université de Lyon</li></orgName></list><tree><country name="France"><noRegion><name sortKey="Ploin, D" sort="Ploin, D" uniqKey="Ploin D" first="D." last="Ploin">D. Ploin</name></noRegion><name sortKey="Chapuis, F" sort="Chapuis, F" uniqKey="Chapuis F" first="F." last="Chapuis">F. Chapuis</name><name sortKey="Denis, A" sort="Denis, A" uniqKey="Denis A" first="A." last="Denis">A. Denis</name><name sortKey="Floret, D" sort="Floret, D" uniqKey="Floret D" first="D." last="Floret">D. Floret</name><name sortKey="Fouilhoux, A" sort="Fouilhoux, A" uniqKey="Fouilhoux A" first="A." last="Fouilhoux">A. Fouilhoux</name><name sortKey="Gillet, Y" sort="Gillet, Y" uniqKey="Gillet Y" first="Y." last="Gillet">Y. Gillet</name><name sortKey="Liberas, S" sort="Liberas, S" uniqKey="Liberas S" first="S." last="Liberas">S. Liberas</name><name sortKey="Lina, B" sort="Lina, B" uniqKey="Lina B" first="B." last="Lina">B. Lina</name><name sortKey="Thouvenot, D" sort="Thouvenot, D" uniqKey="Thouvenot D" first="D." last="Thouvenot">D. Thouvenot</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000258 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000258 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= France
|étape= Analysis
|type= RBID
|clé= Hal:hal-00122898
|texte= Influenza burden in children newborn to eleven months of age in a pediatric emergency department during the peak of an influenza epidemic.
}}
| This area was generated with Dilib version V0.6.33. |  |